Cardiovascular Research Core

The Cardiovascular Research Core (CRC) facility, located within the Biological Resources Laboratory, is a pay-for-service entity that provides advanced surgical and functional assessment services to create and evaluate rodent models of cardiovascular and pulmonary vascular disease. The CRC generates various animal models of pulmonary hypertension, heart failure, myocardial infarction, and other cardiac and pulmonary vascular diseases. By providing training, project consulting, and expert surgical and experimental set-up services, the Core aims to assist scientists and principal investigators in acquiring high-quality and reproducible results for grant applications and manuscripts.

All of our services can be core-assisted, and echocardiography and electrocardiography can be self-directed. To initiate any new service (or Animal Use Protocol or RRC account) please contact us. You can also see what parameters we offer for each functional assessment service by clicking its name above.

All of our services are available for UIC faculty as well as external users. We would be happy to consult with you to plan an experiment, implement one of our rodent models of cardiovascular disease or assist you in developing an animal use protocol and/or grant application.

Please note that both core-assisted and self-directed studies at the CRC are contingent upon prior approval of a PI's Animal Use Protocol by the Institutional Institutional Animal Care and Use Committee (IACUC).

Please visit our RRC website to find out more about our services, the state-of-the-art equipment we utilize, our fee structures and user policies. To initiate a core-assisted service, please fill out and return a request for services form.

NOTE: All work conducted within the CRC, whether core-assisted or unassisted, is contingent upon prior approval of the PI's Animal Use Protocol by the University's Institutional Animal Care and Use Committee

To schedule instrument time, please visit UICore

Surgical Services

  • Transverse Aortic Banding
  • Coronary Artery Ligation
  • Pulmonary vascular permeability assay in mice

 

Functional Assessment Services

  • High Resolution Echocardiography (via Visualsonics' Vevo 2100)
  • Hemodynamics (Pressure or Pressure-Volume Analysis via Scisense's Admittance Technology)
  • IVIS Imaging system to detect inflammation, tumor growth and angiogenesis in preclinical animal models
  • Electrocardiography (ECGenie)

 

Other Services (Dr. Ahlke Heydemann)

  • Treadmill
  • Ex vivo muscle contraction system (papillary muscle function)
  • Plethysmography device (respiratory function)

Please contact Dr. Ahlke Heydemann (312-355-0259 or ahlkeh@uic.edu) for "Other Services"