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Services

Instrumentation and services are available to all researchers inside and outside of the university.

Below are internal rates for UIC, University of Chicago, and Northwestern University. External academic and commercial rates are 1.599X and 2X, respectively.

Please note that rates are subject to change.

All users are responsible for their own laboratory safety training to be current during each use of the core facilities.

Instrument rates for self-users Heading link

SPR (Biacore T200) Internal UIC External Academic Non - Academic Unit
Instrument_Biacore T200_self-run $200.00 $250.00 $400.00 1 day
Instrument_Biacore T200_assisted-run $400.00 $500.00 $800.00 1 day
Service_Trouble shooting/Experimental consults $50.00 $62.50 $100.00 1h
Service_SPR Data Analysis $50.00 $62.50 $100.00 1h
Service_Reagent/screening preparation $50.00 $62.50 $100.00 1h
Service_Compound cherry picking $30.00 $37.50 $60.00 0.5h
Training_Biacore T200_1 person $220.00 $275.00 $400.00 1 person
Training_Biacore T200_2 people in a group $150.00 $187.50 $300.00 1 person
Training_Biacore T200_3 people in a group $130.00 $162.5 $260.00 1 person
Training_Biacore T200_4 people in a group $115.00 $143.75 $230.00 1 person
Training_Biacore T200_5 people in a group $100.00 $125.00 $200.00 1 person
Training_SPR Data Analysis_Basic $50 $62.50 $100 1h
SPR Research project collaboration Contact Hyun Lee (danielhl@uic.edu)

Other Biophysical Instruments Heading link

Description: Understanding the function and structure of biomolecules is crucial in all areas of modern health and life sciences. Characterizing the structure and dynamics of these molecules is essential to understanding the basis of various cellular function, and the Biophysics Core at the Center for Structural Biology is to provide unimpeded access to state-of-the-art and well-maintained biophysics equipment.

Other Instruments Internal UIC External Academic Non-academic Unit
Instrument_AUC $390.00 $500.00 $787.5 per run
Instrument_CD $25.00 $31.25 $50.00 1 hour
Instrument_Emulsiflex $11.25 $14.06 $22.50 1 hour
Instrument_Sonicator $11.25 $14.06 $22.50 30 min
Instrument_ITC $20.00 $25.00 $45.00 1 hour
Instrument_DLS $20.00 $25.00 $25.00 1 hour
Instrument_AKTA purifier FPLC $30.00 $37.50 $60.00 1 hour
Instrument_AKTAxress FPLC $45.00 $62.50 $90.00 1 hour
Instrument_PerkinElmer_Victor3V plate reader $20.00 $25.00 $45.00 1 hour
Instrument_Centrifuge_Sorvall LYNX 4000 $10.00 $12.50 $20.00 30 min
Training_CD $75.00 $95.00 $150.00 1-2 hours
Training_Emulsiflex $50.00 $62.50 $100.00 30 min
Training_Sonicator $50.00 $62.50 $100.00 30 min
Training_DLS $50.00 $62.50 $100.00 30 min
Training_ITC $100.00 $125.00 $200.00
Training_AUC $250.00 $312.50 $500.00 1 person
Training_AKTA purifier $150.00 $187.50 $300.00 1-2 hours
Training_AKTAxpress $175.00 $200.00 $350.00 ~2 hours
Training_ PerkinElmer_Victor3V plate reader $50.00 $62.50 $100.00 30 min
Training_ Data Analysis_CD, DLS, ITC $50.00 $62.50 $100.00 1 hour
Training_ Data Analysis_AUC $100.00 $125.00 $200.00 1-2 hours
User Assistance $50.00 $62.50 $100.00 1 hour
Research projects Contact Hyun Lee (danielhl@uic.edu)

Protein over-expression and Purification Heading link

Description: Large-scale protein purification service is offered to users who need purified proteins for SPR, High-Throughput Screening (HTS), and structural biology (X-ray crystallography and NMR). AKTAxress FPLC enables us to purify four different proteins at a time using a well optimized two-step (HisTrap and Size-exclusion columns) purification protocol.

Protein Purification (Itemized services) Unit cost ($) External Academic Non-academic Unit
Transformation into DH5a (or XL1) cells_Option $50.00 $62.50 $100.00 1 plasmid
Transformation into Rosetta2 (DE3) or BL21 (DE3) cells_Option $50.00 $62.50 $100.00 1 plasmid
2L culture_Protein purification_Affinity column (Ni-NTA_HisTrap)_Basic $1,000.00 $1,250.00 $2,000.00 1 purification
Protein purification_tag-cleavage_reload (Ni-NTA)_Option $250.00 $312.50 $500.00 1 purification
TEV_protease_Option $50.00 $62.50 $100.00 1 purification
SUMO_protease_Option $50.00 $62.50 $100.00 1 purification
Protein_purification_Extra_column_Ion-exchange_Option $250.00 $312.50 $500.00 1 purification
Protein_purification_Extra_column_Size-Exclusion (Superdex 75)_Option $350.00 $437.50 $600.00 1 purification

Macromolecular Structural Biology Heading link

Biophysics core will assist research projects needing macromolecular structure determination and the biophysical characterization of proteins in collaboration using X-ray crystallography (at Argonne) and Cryo-EM (at University of Chicago). Please contact Hyun Lee (danielhl@uic.edu).

Biophysics_Services

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