Mass Spectrometry Core

Beyond making available state-of-the-art, user-friendly facilities and services, the MSC laboratory, located in the Medical Sciences building, enables education, methods development, and new applications development, designed to meet the fast-pace needs of researchers.

Equiped with ICP MS, MALDI-time of flight and other LC-MS systems including Orbitrap Velos Pro, QE-HF, Qtrap, Q-TOF and QQQ MS. Data acquisition/analysis conducted with Xcalibur, ChemStation, Masshunter, Analyst; Mascot, Sequest Sorcerer, Mass Matrix, Scaffold, Maxquant, ProteomeDiscoverer and ProteinPilot.

Routine mass spec services include molecular weight determination, MS^n, LC-MS, high resolution MS, protein identification, PTMs analysis, nano LC-MS/MS and database search, quantitative analysis of small molecule/protein, lilpidomics, metabolomics, proteomics and more.

Notice to all Research Resources Center Customers

In order to minimize COVID-19 spread, the Research Resources Center, Mass Spectrometry Core is implementing the following temporary mandatory guidelines for using this core:

  • All customers entering the core space must wear new, clean gloves
  • If there is a need to remove gloves, wash your hands with soap frequently and for at least 20 seconds. Do not touch your face or other individuals. Replace gloves as soon as possible
  • Instead of shaking hands, exchange greetings with a wave, bow, or nod
  • Try to keep at least one meter/three feet distance between yourself and others
  • Disinfect anything you used during your visit with 70% ETOH after every use
    • Keyboard/mouse
    • Desktop
    • HPLC cover, autosampler door
    • Freezer/refrigerator door handle
  • MSC will use WebEx for project discussion or consulting instead of meeting in person

If you have any flu like symptoms (g., fever, cough, shortness of breath) please do not use the core services. You should stay home and follow the appropriate guidelines as indicated by the Illinois Department of Public Health (IDPH) Р