Publications

1. Gao H, Chen J, Chen T, Wang Y, Song Y, Dong Y, Zhao S, Machado RF. 2019. MicroRNA410 Inhibits Pulmonary Vascular Remodeling via Regulation of Nicotinamide Phosphoribosyltransferase. Scientific Report. 9(1):9949. doi: 10.1038/s41598-019-46352-z.

2. Zhongkai Zhu, Dureti Godana, Ailing Li, Bianca Rodriguez, Chenxin Gu, Haiyang Tang, Richard Minshall, Wei Huang, Jiwang Chen. 2019. Echocardiographic Assessment of Right Ventricular Function in Experimental Models of Pulmonary Hypertension. Pulmonary Circulation. 9(2):2045894019841987. doi: 10.1177/2045894019841987.

3. Oliveira SDS, Chen J, Castellon M, Mao M, Usha Raj J, Comhair S, Erzurum S, Silva CLM, Machado RF, Bonini MG, Minshall RD. 2019. Injury-Induced Shedding of Extracellular Vesicles Depletes Endothelial Cells of Cav-1 (Caveolin-1) and Enables TGF-β (Transforming Growth Factor-β)-Dependent Pulmonary Arterial Hypertension. Arterioscler Thromb Vasc Biol. 39(6):1191-1202.

4. Jingbo Dai, Qiyuan Zhou, Jiwang Chen, Megan Rexius-Hall, Jalees Rehman, and Guofei Zhou. 2018. Alpha-Enolase Regulates the Malignant Phenotype of Pulmonary Artery Smooth Muscle Cells via the AMPK-Akt pathway. Nature Communication. 9(1):3850.

5. DeLalio LJ, Keller AS, Chen J, Boyce AKJ, Artamonov M, Askew-Page HR, Keller TCS 4th, Johnstone SR, Weaver RB, Good ME, Murphy S, Best AK, Mintz EL, Penuela S, Greenwood I, Machado RF, Somlyo AV, Swayne LA, Minshall R, Isakson BE. 2018. Interaction Between Pannexin 1 and Caveolin-1 in Smooth Muscle Can Regulate Blood Pressure. Arterioscler Thromb Vasc Biol. 38(9):2065-2078.

6. Dai Z, Zhu MM, Peng Y, Machireddy N, Evans CE, Machado R, Zhang X, Zhao YY. 2018. Endothelial and Smooth Muscle Cell Interaction via FoxM1 Signaling Mediates Vascular Remodeling and Pulmonary Hypertension. Am J Respir Crit Care Med. 198(6):788-802.

7. Lv Y, Kim K, Sheng Y, Cho J, Qian Z, Zhao YY, Hu G, Pan D, Malik AB, Hu G. 2018. YAP Controls Endothelial Activation and Vascular Inflammation Through TRAF6. Circ Res.123(1):43-56.

8. Eichner M, Purcell JE, Fortman JD. 2018. The effects of intracage ammonia on markers of pulmonary endothelial integrity in mice housed in static microisolator cages. J Am Assoc Lab Anim Sci 57: 18-23.

9. Chen J, Sysol JR, Singla S, Zhao SP, Yamarua A, Valdez-Jasso D, Abbasi T, Shioura KM, Sahni S, Reddy V, Sridhar A, Camp SM, Tang H, Gao H, Ye SQ, Comhair S, Dweik R, Hassoun P, Yuan J X-J, Garcia JGN, Machado RF. 2017. Nicotinamide Phosphoribosyltransferase Promotes Pulmonary Vascular Remodeling and is a Therapeutic Target for Pulmonary Arterial Hypertension. Circulation. 135(16):1532-1546.

10. Suellen Oliveira, Maricela Castellon, Jiwang Chen, Marcelo Bonini, Xiaowu Gu, Michael Elliott, Roberto Machado, and Richard Minshall. 2017. Inflammation-induced caveolin-1 and BMPRII depletion promotes endothelial dysfunction and TGFβ-driven pulmonary vascular remodeling. Am J Physiol Lung Cell Mol Physiol. 312(5):L760-L771.

11. J. Coburn, J. Harris, A. D. Zakharov, J. Poirier, N. Ikegaki, A. Kajdacsy-Balla, M. Pilichowska, A. V. Lyubimov, H. Shimada, D. L. Kaplan, and B. Chiu. 2017. Implantation of chemotherapy-loaded controlled release silk protein materials within neuroblastoma tumor. International Journal of Cancer, 140(3):726-735.

12. J. C. Harris, E. Herrero-Garcia, A. Russo, A. Kajdacsy-Balla, J. P. O'Bryan, and B. Chiu. 2017. Silencing Intersectin 1 slows orthotopic neuroblastoma growth in mice. Journal of Pediatric Hematology/Oncology, 39(8):e413-e418.

13. J. Coburn, J. Harris, R. Cunningham, J. Zeki, D. L. Kaplan, and B. Chiu. 2017. Manipulation of variables in local controlled release vincristine treatment in neuroblastoma. Journal of Pediatric Surgery, 52(12):2061-2065.

14. R. Teshiba, R. Matsuno, L. L. Wang, X. X. Tang, B. Chiu, J. Zeki, J. Coburn, K. Ornell, A. Naranjo, C. V. Ryn, W. B. London, M. D. Hogarty, J. M. Gastier-Foster, A. T. Look, J. R. Park, J. M. Maris, S. L. Cohn, R. C. Seeger, S. Asgharzadeh, N. Ikegaki, and H. Shimada. 2017. MYC-family protein overexpression and prominent nucleolar formation represent prognostic indicators and potential therapeutic targets for aggressive High-MKI Neuroblastomas: A Report from the Children’s Oncology Group. Oncotarget, 9(5):6416-6432.

15. Ryba DM, Li J, Cowan CL, Russell B, Wolska BM, Solaro RJ. 2017. Long-Term Biased β-Arrestin Signaling Improves Cardiac Structure and Function in Dilated Cardiomyopathy. Circulation. 135(11):1056-1070.

16. Dai Z, Li M, Wharton J, Zhu MM, Zhao YY. 2016. Prolyl-4 Hydroxylase 2 (PHD2) Deficiency in Endothelial Cells and Hematopoietic Cells Induces Obliterative Vascular Remodeling and Severe Pulmonary Arterial Hypertension in Mice and Humans Through Hypoxia-Inducible Factor-2α. Circulation 133(24):2447-58.

17. Yangbasai Dong, Bing Liu, Hui Gao, Roberto Machado, Jiwang Chen. 2016. Measurement of the right ventricular systolic pressure in rats for studies of pulmonary arterial hypertension: a visualized protocol. Newpubli. 1 (e0006).

18. Sun M, Ramchandran R, Chen J, Yang Q, Raj JU. 2016. Smooth Muscle Insulin-like Growth Factor-1 Mediates Hypoxia-induced Pulmonary Hypertension in Neonatal Mice. Am J Respir Cell Mol Biol. 55(6):779-791.

19. Indu Venugopal, Sebastian Pernal, Taylor Fusinatto, David Ashkenaz and Andreas Linninger. 2016. Quantum Dot Conjugated Magnetic Nanoparticles for Targeted Drug Delivery and Imaging. Nano Biomed. Eng. 8(1), 24-38.

20. J. Harris, A. Kajdacsy-Balla, B. Chiu. 2016. Creation of a murine orthotopic hepatoma model with intra-abdominal metastasis.” Gastroenterology and Hepatology: from Bed to Bench, 9(3):174-179.

21. J. Harris, J. Coburn, A. Kajdacsy-Balla, D. L. Kaplan, B. Chiu. 2016. Sustained delivery of vincristine inside an orthotopic mouse sarcoma model decreases tumor growth. Journal of Pediatric Surgery, 51(12):2058-2062.

22. Wilder T, Ryba DM, Wieczorek DF, Wolska BM, Solaro RJ. 2015. N-acetylcysteine reverses diastolic dysfunction and hypertrophy in familial hypertrophic cardiomyopathy. Am J Physiol Heart Circ Physiol. 309(10):H1720-30.