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Biophysics Core

Understanding the function and structure of biomolecules is crucial in all areas of modern health and life sciences.  Characterizing the structure and dynamics of these molecules is essential to understanding the basis of various cellular function, and the Biophysics Core at the Center for Structural Biology is to provide unimpeded access to state-of-the-art and well-maintained biophysics equipment.

The Biophysics Core, located in the Center for Structural Biology, offers three main categories of research and services: characterization of macromolecules using various biophysical instruments (SPR, ITC, DLS, CD & AUC), large-scale protein production, and macromolecular structural biology using X-ray crystallography and Cryo-EM in collaboration.

The Biophysics Core houses a suite of various biophysical instruments and has a fully equipped wet-laboratory for molecular cloning, recombinant protein expression, and protein purification. Large-scale protein purification service is also offered to users who need purified proteins for SPR, High-Throughput Screening (HTS), and structural biology.

For more information on the Biophysics Core, please click here.

Notice to all Research Resources Center Customers

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Biophysics Core MP, ITC and SPR Training Sessions in July

The Biophysics Core is offering training sessions throughout July for the Refeyn Two Mass Photometer, MicroCal PEAQ-ITC and the Biocore T200 SPR instruments.  Training dates and registration information are located here.  

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